[TEZ-070]发行于2010-12-28时长90分钟出品商是信州書店,TEZ-070作品种子搜索下载,[DGKS-002]发行于2011-02-03时长60分钟出品商是ジャネス,DGKS-002作品种子搜索下载
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[TEZ-070]发行于2010-12-28时长90分钟出品商是信州書店,TEZ-070作品种子搜索下载,[DGKS-002]发行于2011-02-03时长60分钟出品商是ジャネス,DGKS-002作品种子搜索下载
[SNS-411]发行于2010-07-28时长88分钟出品商是信州書店,SNS-411作品种子搜索下载,[DGKS-001]发行于2011-02-02时长62分钟出品商是ジャネス,DGKS-001作品种子搜索下载
[DPMK-007]发行于2011-09-25时长117分钟出品商是ユープランニング,DPMK-007作品种子搜索下载,[DGKS-003]发行于2008-04-05时长54分钟出品商是ジャネス,DGKS-003作品种子搜索下载
哺乳动物的DGKs作为由十种亚型构成的蛋白质家族,根据它们的结构特征将其分为五型。这些亚型可以通过已知和/或预测功能的各种调节结构域,清楚地表明其不同的功能和调节机制。目前大量的研究表明DGKs可通过调节机体的免疫功能及调控多种肿瘤相关信号通路从而对肿瘤细胞的增殖、凋亡、转移起作用。本文就DGKs与肿瘤之间关系...
The discovery was made by studying mice that had been engineered to lack diacylglycerol kinases (DGKs). Although T cells from these knock-out mice were normal in most respects the induction of tolerance was impaired. When DAGs could not be chemically altered because the DGKs were absent, the ...
通过 DGKs 介导将 DAG 专换成 FA使得 DAG信号终止1261o新研究表明,DGKs 寸于调节兴奋性神经元内的DAG 水平和树突棘的 维持起到了重要作用12728。在有 DGK 时崔化活性和 PSD-95结合的条件下,DGKs 过度表达可 增加树突棘的密度。除此之外,还有多种分子参与维持树突棘可塑性,如 Cofilin可以使肌动蛋白纤维解聚...
Diacylglycerol kinases (DGKs) are important regulators of cell signaling and have been implicated in human malignancies. Whether epigenetic alterations are involved in the dysregulation of DGKs in cancer is unknown, however. We therefore analyzed methyla
The role of type I diacylglycerol kinases (DGKs) in the regulation of insulin secretion was investigated in MIN6 β-cells. In intracellular Ca2+concentration ([Ca2+]i) measurement experiments, 1 μM R59949, a type I DGK inhibitor, and 10 μM DiC8, a diacylglycerol (DAG) analog, amplifie...
Tocris Summary for DGKK Gene Diacylglycerol kinases (DGKs) are a group of ten enzymes that metabolize 1,2,diacylglycerol (DAG) to produce phosphatidic acid (PA). They all contain a conserved C'-terminal catalytic domain and two cysteine-rich Zn2+-finger motifs with varied regulatory domains....
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Type I DGKs α and β differ markedly in tissue distribution; DGKα is one of the most commonly expressed DGKs and particularly enriched in the brain, lungs, and white blood cells, while DGKβ is found at lower levels and predominantly in nerves and the brain (5,6). This suggests poten...