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文献链接：https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00227 11. Discoveryof M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of theMenin–MLL Interaction with Strong In Vivo Antitumor Activity 荐读...

文献连接：https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00176 2. Inhibiting Matrix Metalloproteinase-2 Activation by Perturbing Protein–Protein Interactions Using a Cyclic Peptide 荐读：我们报道了一种循环肽，其在低纳...

3.KnudsenLBetal.JMedChem2000 ;43:1664–1669.4.Degnetal.Diabetes2004;53:1187–94利拉鲁肽在皮下组织中吸收 延迟,有效延长半衰期血液中的单体与白蛋白结合避免被肾脏快速清除肽链脂肪酸利拉鲁肽在药物制剂和皮下组织中七聚体结构St...

doi: 10.1016/j.immuni.2023.03.002 Yam, Andrew O., Bailey, Jacqueline, Lin, Francis, Jakovija, Arnolda, Youlten, Scott E., Counoupas, Claudio, Gunzer, Matthias, Bald, Tobias, Woodruff, Trent M., Triccas, ...

参考文献 Tong Zhao.NovelHuman Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates withFavorable Druggability.J.Med.Chem.2020(DOI: 10.1021/acs.jmedchem.0c00223)

Marinelli.Interfering with the Tumor–Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors.Journal of Medicinal Chemistry2021,64(21) , 16020-16045.https://doi.org/10.1021/acs.jmedchem...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c02000. Biochemicals; experimental apparatus; synthetic methods; NMR, ESI-MS, HPLC, UV–vis absorption spectra; RO...