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The absence of miR-146a in Tregs exerted a mild suppressive effect, prolonging the allograft MST from only 7 days to 11 days in animal models. We investigated the regulatory effect of miR-146a-deficient Tregs on CD4+T cells in vitro to explain this phenomenon. Subsequently, in the co-cultur...

Herein we report a mild, transition-metal-free, highly diastereoselective Lewis acid catalyzed methodology toward the synthesis of isoxazolidine-based diazo compounds from the reaction between vinyldiazo esters and nitrones. Interestingly, the isoxazolidine products were identified to have contrasting diaste...

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Carola-Bibiane Schoenlieb  –  Carola Schönlieb  –  Carola B. Schönlieb '20 '10 '00 Trier Dagstuhlby year by type> Home > Persons Person information affiliation: University of Cambridge, UK Refine list refinements active! zoomed in on ?? of ?? records dismiss all constraints...

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MicroRNAs (miRNAs) have recently been shown to play important roles in development of the immune system and in fine-tuning of immune responses. Human miR-146 family members are known as inflammation-inducible miRNAs involved in negative feedback regulati

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