PDX-012 搜索结果

[PDX-012]发行于2003-06-08时长60分钟出品商是トライハート,PDX-012作品种子搜索下载,森高千春[FSV-006]发行于2003-06-15时长90分钟出品商是h.m.p,FSV-006作品种子搜索下载

A1 from INS-1 nuclear extracts specifically pulled down PDX-1 and MafA, as shown by Western Blot analysis with well-characterized anti-PDX-1 or anti-MafA antibodies. These findings unequivocally demonstrate that HMGA1 physically interacts with PDX-1 and MafA bothin vitroandin vivo, and suggest ...

To generate “P0” PDX mice, fresh patient tumors obtained directly from surgery are used to ensure highest tumor cell viability to maximally improve PDX engraftment efficacy (106,136,137). The transplantation is either done subcutaneously, into the skin, or orthotopically, into the organ where t...

The homeodomain transcription factor IPF1/PDX1 exerts a dual role in the pancreas; Ipf1/Pdx1 global null mutants fail to develop a pancreas whereas conditional inactivation of Ipf1/Pdx1 in β-cells leads to impaired β-cell function and diabetes. Although several putative target genes have been...

In addition, a novel humanized mouse model, named PDXv2.0, was recently constructed by Dr. Jonas A. Nilsson's group through adoptive transfer ofin vitroexpanded human tumor infiltrating lymphocytes (TILs) into the PDX mice that host the tumor collected from the same patients (106). They showe...

CTM012是一种具有同类最优潜力的新一代T细胞激动性抗体,于报告期内已进入IND申报研究阶段;计划将于2024年申报IND。 9、WT1-TOPAbody WT1-TOPAbody是一款基于TOPAbody平台与百奥赛图联合开发的靶向WT1/CD3/4-1BB三抗,WT1为胞内靶点,降解为多肽后递呈到MHC-I上,在许多血液瘤和实体瘤中高表达;通过CD3和4-1...

Forward programming of hiPSCs towards beta-like cells using Ngn3, Pdx1, and MafA Introduction Diabetes is a major metabolic disease that affects not only people around the world but also human’s companion animals, mostly dogs and cats1,2,3. Pathophysiologically, it is classified into two main...