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[SHU-087]发行于2011-11-04时长59分钟出品商是映天,SHU-087作品种子搜索下载,手塚莉絵[BMC-025]发行于1993-12-12时长47分钟出品商是h.m.p,BMC-025作品种子搜索下载

PMID: 14604670 DOI: 10.1016/j.bmc.2003.08.025 Abstract We examined the properties of RNA analogues containing 2'-deoxy-2'-alpha-fluorouridine (1) or 2'-O-methyluridine (2) as inhibitors against human RNase L, that cleaves a single-stranded RNA in the presence of 2',5'-linked ...

PMID: 25009002 DOI: 10.1016/j.bmc.2014.06.025 Abstract We report herein the discovery, structure guided design, synthesis and biological evaluation of a novel class of JAK2 inhibitors. Optimization of the series led to the identification of the potent and orally bioavailable JAK2 inhibitor 28 (...

Current lab-on-a-chip (LoC) devices are assay-specific and are custom-built for each single experiment. Performing an experiment requires scientists or engineers to go through the time-consuming process of designing, fabricating, and testing a chip before conducting the actual experiment. This prol...

Abstract The H- and N-Ras GTPases are prominent examples of proteins, whose localizations and signalling capacities are regulated by reversible palmitoylations and depalmitoylations. Recently, the novel small molecule inhibitor palmostatin B has been described to inhibit Ras depalmitoylation and to rev...